Product

Levodopa

Overview

Levodopa is a prodrug of dopamine (DA), which itself has no pharmacological activity. It enters the center through the blood-brain barrier and is converted into DA by dopa decarboxylase to exert pharmacological effects.

Specification:
  • Drug name: levodopa

  • Foreign name: Levodopa

  • Alias(S)-2-amino-3-(4-hydroxyphenyl)propionic acid

  • Type of drugchemical

  • Chemical formulaC9H11NO4

  • Molecular weight197.188

  • Appearancewhite or off-white crystalline powder

  • CAS59-92-7

  • EINECS200-445-2

  • Density1.47 g/cm³

  • Melting point276 to 278 ℃

  • Boiling point448.4 ℃

  • Flash point225.0 ℃

  • water solubilitysoluble

  • Safety descriptionS26, S36, S24/25

  • Hazard symbolsR22, R36/37/38, R20/21/22


Functions:
  1. Parkinson's disease (essential tremor paralysis). 

    Symptomatic Parkinsonism (non-drug-induced tremor paralysis syndrome) after encephalitis or combined with cerebral arteriosclerosis and carbon monoxide and manganese poisoning of the central nervous system. It can reduce the symptoms of tremor paralysis, improve muscle tension, and make limb movements more normal. The effect is better for mild and moderate patients, and worse for severe or elderly patients.

  2. Hepatic encephalopathy. 

    It can make the patient wake up and improve the symptoms. Hepatic encephalopathy may be related to the abnormality of the central transmitter dopamine. After taking it, it can improve the central function and work. It is also believed that levodopa can improve the brain's tolerance to ammonia, but does not improve liver damage and liver function.

  3. Neuralgia. 

    Taken early to relieve neuralgia.

  4. Hyperprolactinemia. 

    It can inhibit the thyrotropin-releasing hormone in the hypothalamus and stimulate the prolactin-releasing inhibitor, thereby reducing the secretion of prolactin. It is used to treat hyperprolactinemia and has a certain effect on galactorrhea.

  5. Alopecia. 

    The mechanism may be to increase the concentration of catecholamines in the blood to tissues, which promotes hair growth.

  6. Promote the growth and development of children.

    It can accelerate the growth and development of children's bones by promoting the secretion of growth hormone. Treatment of children with hypopituitarism.


Logistics Transports:

物流

All comments
Pictures
Praise rate: 0.0%