Sialic acid (SA), scientifically called "N-acetylneuraminic acid", is a naturally occurring carbohydrate. It was originally isolated from the submandibular gland mucin, hence the name. Sialic acid is usually present in the form of oligosaccharides, glycolipids or glycoproteins. In the human body, the brain has the highest sialic acid content. The content of sialic acid in the gray matter of the brain is 15 times that of internal organs such as liver and lung. The main food source of sialic acid is breast milk, which is also found in milk, eggs and cheese.

It was originally isolated from the submandibular gland mucin, hence the name. Sialic acid is usually present in the form of oligosaccharides, glycolipids or glycoproteins. In the human body, the brain has the highest sialic acid content. The content of sialic acid in the gray matter of the brain is 15 times that of internal organs such as liver and lung. The main food source of sialic acid is breast milk, which is also found in milk, eggs and cheese.

The main food source is breast milk, which is also present in milk, eggs/cheese and bird's nest, which is also known as bird's nest acid due to the high amount of sialic acid in bird's nest.

One of the reasons for the unique efficacy of bird's nest is that bird's nest has been confirmed by today's medical community to be rich in a unique neuraminic acid - bird's nest acid, which is the main biologically active ingredient in traditional Chinese food bird's nest.

1. Natural product extraction method: The content of sialic acid in natural raw materials is relatively low, and the composition is more complicated than that in fermentation broth, and the separation and purification process is complicated.

2. Microbial fermentation method: polysialic acid exists on the surface of a few bacteria in the form of capsules. When these bacteria are cultured in solids, polysialic acid attaches to the cell surface in the form of capsules; when cultured in liquids, polysialic acid is released into the fermentation broth in the form of mucus. After acid hydrolysis or enzymatic hydrolysis of polysialic acid, sialic acid can be obtained by separation and purification, which provides an industrial basis for the preparation of sialic acid drugs.

3. Biosynthesis: Using relatively cheap N-acetyl glucose as raw material, sialic acid was synthesized in an enzyme membrane reactor through a two-step enzymatic reaction of isomerase and sialyl aldolase.

   For example, N-acetylneuraminic acid monomer is prepared by means such as microbial fermentation method, extraction method, enzymatic depolymerization and saliva method, and finally high-purity monomer dry powder or hydrate crystal can be obtained by crystallization.

Sialic acid primarily promotes brain development and cognitive function, but it also has many other beneficial effects.

Sialic acid can effectively promote the development and functional repair of nerve cells, epithelial cells and immune cells, thereby improving immunity.

Sialic acid can further modulate the immune system in a variety of ways through siglecs (sialic acid-binding immunoglobulin-type lectins) and affect antibody-mediated pathogen clearance through complement activation.

Sialic acid also acts against influenza through sialylation of antibody immunoglobulin A (IgA), which interferes with the cell surface attachment of influenza A virus and leads to the mediation of IgA antiviral activity.

Sialylation of IgA also acts as an anti-inflammatory and has been used for decades as a treatment for many autoimmune diseases.

Sialic acid is also a natural MMP-1 inhibitor. By reducing the expression and activity of MMP-1, sialic acid can restore senescent cells to a normal state and maintain cellular stability. This critically reduces the rate of cell decline and extends the lifespan of skin cells, an important part of preventing the signs of aging.

1. Moisturizing: can help the skin retain moisture.

2. Whitening: can effectively inhibit the production of melanin in skin cells.

3. Anti-inflammatory and acne-removing: It can speed up the subsidence of acne and inflammation on the skin.

4. Anti-aging: N-acetylneuraminic acid is an important component of glycoproteins on the cell membrane, which has a significant effect on intercellular adhesion and ensuring cell elasticity.

   
   

   Mainly used in soaps, facial cleansers, shower gels, toners, skin care gels, skin lotions, skin creams, serums, eye creams, masks, mascaras or lipsticks.

Packaging:

• 1-5kg: The inner layer is an ordinary plastic sealed bag, the outer layer is an aluminum foil bag, and an outer carton is used.

• More than 5kg: inner double PE bag, outer paper drum (round and square) or paper drum with iron ring.

Storage conditions:

• Store in a ventilated and dry environment, avoid direct sunlight and high temperature conditions.